One of the interesting things that has happened in extant genetic codes is the discoveries that have to do with the degeneracy of the genetic code—the existence of several different sequences of bases in the messenger RNA molecule that can cause the same amino acid segment to be incorporated in the protein under construction. For example, the evidence strongly suggests that the amino acid arginine can be evoked by any one of three messenger RNA triplets CGC, AGA, and UCG. The related inference also appears to be correct: that three different types of transfer RNA molecule, each capable of carrying the amino acid arginine, correspond to these three messenger RNA triplets. Such degeneracy in the code is compatible with the fact that 4 X 4 X 4, or 64, different messenger or transfer RNA triplet combinations can be made of the 4 bases of the nucleic acid molecule, whereas only 20 amino acids must be specified by the various combinations. The evidence to this point suggests that every one of the 64 possible combinations may ultimately be found to be “meaningful” in the sense of specifying one or another of the 20 amino acid constituents of the end-product protein molecules. It should be noted that this kind of degeneracy does not lead to ambiguity in the genetic code. To be sure, it means that messenger RNA molecules with different base sequences can govern the production of the same kind of protein. And the existence of such alternative “words” within the genetic language suggests that different species of organisms may employ somewhat different dialects in the nuclear books of instruction with which they control their cellular chemistry. Nevertheless, the code could still be universal in the sense that a given messenger RNA molecule, if capable at all of operating the genetic mechanisms of different types of foreign organisms, would always produce the same kind of protein molecules. #RandolphHarris 1 of 21

Not only did Bonner’s successful crossbreeding of the genetic mechanisms of pea plants and E. coli cell-free extracts in experiments with synthetic messenger RNA has provided further confirming evidence. While much less work has been done with mammalian than with bacterial components, it has at least been established that the messenger RNA triplets that evoke specific amino acids in the finally fabricated protein molecules are the same for mammalian as for bacterial systems in the case of the half-dozen kinds of messenger nucleic acid that have been tested. In general, while making allowance for some degree of variation from species to species in the details of the genetic mechanisms, biochemists today are confident that the genetic code has essentially been “broken”—that they are on the point of being able to line up every possible messenger RNA triplet with a particular amino acid in the resulting protein molecule. However, the specific sequence of amino acid segments in the manufactured protein molecules determine their catalytic properties and therefore controls the specific set of chemical reactions that take place in the cell. Therefore, the solution of the genetic code in this way implies the ultimate ability of the scientist to “read” the molecules of messenger RNA (or the nuclear DNA which produces them) and thereby learn the properties of the cell whose metabolism they control—whether the cell is to have the properties of pea plant or intestinal bacillus, for example. Inasmuch as the higher organisms, including humans, are believed to employ the same system of genetic control (plus a few complications yet to be treated), the implications of this work are that one day the biochemists are now able to determine the colour of eyes and shape of the nose of a yet-to-be-developed human individual by analysis of the structure of the nucleic acid molecules in the cells of the embryo! #RandolphHarris 2 of 21

Before we move on to some of the additional complexities that characterize the structure and metabolism of higher organisms, we should make sure that we understand how the discussion how all of this information contributes to our basic thesis as to the purely physical origins of life. The experimental evidence reported here can only strengthen our faith in the soundness of our nonvitalistic philosophy; for strong support for the thesis of the fundamentally physical nature of the life processes is provided by the success of the biochemists in extracting from living cells the pertinent nucleic acid/enzyme apparatus and in stimulating it to perform its architectural functions by means of the addition of nucleic acid from other organisms. Ans the successful employment of human-made chemicals for this purpose even verges on the dramatic in its demonstration of the workability of our physical explanations. Not even the evidence for the similarity of the principal features of the genetic mechanisms in all forms of life is particularly disturbing. To be sure, this might at first glance appear to be more reconcilable with the vitalistic view of the supernatural purposiveness of life than with the materialistic view that everything has happened as the result of the blindly probabilistic physical laws of the Universe. However, there is really no great problem in imagining evolutionary developments that could have led to a considerable degree of ultimate standardization in the nucleic acid/enzyme mechanisms. And such evidence of variety as the degeneracy of the genetic code, with the accompanying implication of divergence from species to species in some of the details of the genetic mechanism, seems comfortably consistent with our views of the normal consequences of the evolutionary process. #RandolphHarris 3 of 21

As we address ourselves to some of the further complexities that characterize modern higher organisms, we shall find that our considerations will continue to be intimately involved with the genetic mechanisms that have occupied so much of our attention to this point. We shall not be able to escape being enormously impressed by their overriding power and importance in the phenomena of life. While evolution is clearly the great technique employed by nature for developing its biological novelties, we shall find it easy to conclude that the genetic mechanisms may constitute the most ingenious and important invention yet achieved by the use of that technique. Now, looking ahead. Did you know that your DNA determines your reaction to caffeine? Caffeine is widely consumed in foods and beverages and is also used for a variety of medical purposes. Despite its widespread use, relatively little is understood regarding how genetics affects consumption, acute response, or the long-term effects of caffeine. Twin studies find the heritability of caffeine-related traits to range between 0.36 and 0.58. Analysis of poly-substance use shows that predisposition to caffeine use is highly specific to caffeine itself and shares little common disposition to use of other substances. Genome association studies link variations in adenosine and dopamine receptors to caffeine-induced anxiety and sleep disturbances. Polymorphism in the metabolic enzyme cytochrome P-450 is associated with risk of myocardial infraction in caffeine users. Modeling based on twin studies reveals that genetics plays a role in individual variability in caffeine consumption and in the direct effects of caffeine. Both pharmacodynamic and pharmacokinetic polymorphisms have been linked to variation in response to caffeine. These studies may help guide future research in the role of genetics in modulating the acute and chronic effects of caffeine. #RandolphHarris 4 of 21

Caffeine is the World’s most widely used stimulant. Nearly 90 percent of adults in the United States of America alone consume an estimated 30 million pounds of this psychoactive substance annually. It is the most consumed psychoactive substance in the World.  Seventy-five percent of this caffeine is taken in the form of coffee (from the coffee bean); the rest is consumed in tea (from the tea leaf), cola (from the kola nut), chocolate (from the cocoa bean), and numerous prescription and over-the-counter medications, such as Excedrin. Caffeine’s popularity Worldwide can be attributed to its ability to promote wakefulness, enhance mood and cognition, and produce stimulatory effects. It is used clinically to treat premature neonatal apnea and as an analgesic adjuvant. Around 99 percent of ingested caffeine is absorbed by the body and reaches its peak concentration with an hour. It acts as a stimulant of the central nervous system, again producing a release of the neurotransmitters dopamine, serotonin, and norepinephrine in the brain. Thus it increases arousal, mild euphoria, alertness, enhanced cognitive performance and motor activity and reduces fatigue. It also disrupts the performance of motor tasks and may interfere with sleep. Finally, it increases the rate of breathing and gastric acid secretions in the stomach. More than two to three cups of brewed coffee (250 milligrams of caffeine) can produce caffeine intoxication, which may include such symptoms as restlessness, nervousness, anxiety, stomach disturbances, twitching, and increased heart rate. Grand mal seizures and fatal respiratory failure or circulatory failure can occur at doses greater than 10 grams of caffeine (about 100 cups of coffee), but there is a decreased risk in neurodegenerative disorders. Many people who suddenly stop or cutback on their usual intake of caffeine experience withdrawal symptoms—even some individuals whose regular consumption is low (two and a half cups of coffee daily or seven cans of cola). #RandolphHarris 5 of 21

It is likely that several factors contribute to individual differences in responses to caffeine, including demographic and environmental factors such as age, other drug use, circadian factors, and sleep hygiene. One important source of variability that has received some attention in the recent year is genetic predisposition. There is growing evidence that individual differences in caffeine response or caffeine consumption are related to genetic factors. Genetic factors may influence responses to caffeine directly, by altering acute or chronic reactions to the drug, or indirectly, by affecting other psychological or physiological processes that are related to the drug effect, such as sensitivity to anxiety, rewarding and reinforcing effects of substances in general, or related personality traits. Finally, genes can also alter the body’s adaptive responses to long-term caffeine use. The biological mechanisms of these possible sources of variation likely involve interactions at multiple sites. One study had adult subjects consume their usual caffeine-filled drinks and foods for two days, then abstain from such foods for two days while taking actual caffeine pills. More subjects experienced headaches (52 percent), depression (11 percent), anxiety (8 percent), and fatigue (8 percent) during the two-day placebo period then during the caffeine periods. In addition, subjects reported using more unauthorized medications (13 percent) and performed experimental tasks more slowly during the placebo period than during the caffeine periods. Genetic contribution to caffeine consumption changes through different stages in life. It appears that genetic contribution becomes more pronounced throughout adolescence and then stabilized during adulthood. Researchers found that genetics influence individual sensitivity to caffeine toxicity, tolerance, and withdrawal in female twins. On average the woman reported slightly higher level of caffeine-induced insomnia and greater sleep disturbances in general health than men. #RandolphHarris 6 of 21

Epidemiological studies indicate that smokers drink more coffee than nonsmokers, but it is not clear whether these associations are related to genetic factors or to drug interactions, social conditioning, or other variables. One approach to solving this question is to correlate the use of caffeine to other drugs and using the common pathway model and mapping the genetic contribution to a common joint use factor and substance-specific factors. Using this technique, researchers found that the heritability for coffee use overlapped with that of nicotine and alcohol, though 0.72 of the total heritability was specific to caffeine, which was considerably higher than that for nicotine and alcohol. Investigators often assess caffeine’s impact by measuring coffee consumption, yet coffee also contains other chemicals that may be dangerous to one’s health. Thus, although some studies hint at links between caffeine and cancer (particularly pancreatic cancer), the evidence is not conclusive. Similarly, studies demonstrating correlations between caffeine and heart rhythm irregularities (arrhythmias) or high cholesterol levels are not fully reliable. Caffeine does, however, appear to cause at least a slight increase in blood pressure over time in regular users and a larger but short-lived increase during the first few days of consumption by new users. As public awareness of these possible health risks has increased, caffeine consumption has declined. Around half of Americans now drink coffee daily, whereas 80 percent did so in 1983. Heavier caffeine users appear to be more influenced by genetics than lighter caffeine users. People who tend to consume more alcohol also tend to drink more coffee. Genetic association studies have been used to identify specific genes that are responsible for the heritable components of these caffeine-related traits. Caffeine and its metabolites belong to the methylxanthine class, which are structurally similar to cyclic nucleotides, and interact with cyclic nucleotide phosphodiesterases. #RandolphHarris 7 of 21

Caffeine is absorbed rapidly and completely from the gastrointestinal tract. It is metabolized by cytochrome P-450 enzymes, which represent the rate-limiting step for plasma clearance, and its elimination follows first-order kinetics. P-450 1A2, which is coded for by gene CYP1A2, is the primary isoenzyme responsible for the demethylation of caffeine into dimethylxanthine metabolites paraxanthine, theobromine, and theophylline. Each of these metabolites is subjected to further demethylation into monimethylxanthines. Variation in the CYP1A2 activity, both within and between individuals, represents a major source of variability in pharmaco-kinetics of caffeine. The clearance of caffeine can vary to up to 40-fold within and between individuals. Notable exogeneous factors that affect clearance include numerous drugs, medications, and smoking status, as well as caffeine itself. Endogenous factors include pregnancy, ethnicity, and genetics. Asian and African populations, for instance, appear to metabolize caffeine at slower rate than Caucasians. Genetic variations in a number of neurotransmitter functions could influence responses to caffeine. Because 10 grams of caffeine can be fatal, the substance is classified as a medical poison. The greatest danger for most of us is not that our aim is too high and we will miss it, but that it is too low and we will reach it. A leader is someone who has the capacity to create a compelling vision that takes people to a new place. In 1783 Washington sent a circular letter to the States, describing the situation of the new nations as he saw it. “We have equal occasion to felicitate ourselves,” he said, “on the lot which Providence has assigned to us, whether we view it in a natural, a political, or moral point of light.” #RandolphHarris 8 of 21

He pointed to the natural resources of the new nation, its independence and freedom, the Age of Reason during which it had come of age, an age of “the free cultivation of letters, the unbounded extension of commerce, the progressive refinement of manners, the growing liberality of sentiment, and above all the pure and benign light of Revelation….if these citizens,” he concluded, “should not be completely free and happy, the fault will be certainly their own. Such is our situation and such are our prospects.” It is hard to read these sentences without agitation and tears, for they are simply true and simply patriotic. In the next generations, almost to our own times, patriotic rhetoric did not cease to sound, more pompously and falsely, but never without a core of truth. There was always something special in the American destiny to be proud of. In 1825 it was the broad democracy. In 1850 it was the magnificent spread and settlement from coast to coast. In 1875, the material progress, the cable and the Pacific railroad, the building of modern industrialism. In 1900, America was the melting pot, the asylum of the poor and the oppressed. In our century, the patriotic rhetoric began to be unbelievable—not by accident, for foreign wars (1898 and 1917) are incompatible with reasonable rhetoric. In recent decades there has been almost a surcease of such speech. Even references to the American Way, free enterprise, high production, and the economy of abundance have finally died out, because they call up the idea of tail fins and TV commercials. Highbrow journalists mention the American Way with scorn. Our case is astounding. For the first time in recorded history, the mention of country, community, place has lost its power to animate. Nobody but a scoundrel even tries it. Our rejection of false patriotism is, of course, itself a badge of honour. However, the positive loss is tragic and I cannot resign myself to it. #RandolphHarris 9 of 21

A man has only one life and if during it he has no great environment, no community, he has been irreparably robbed of a human right. This loss is damaging especially in growing up, for it deprives outgoing growth, which begins with weaning from Mother and walking out of the house, of the chance of entering upon a great and honourable scene to develop in. Culture is, first of all, city and patriotic culture. Patriotism is the culture, we come with a fatal emptiness to the humane culture of science, art, humanity and God; and this emptiness results in the best people not turning back, like Plato’s philosopher who has emerged from the cave, to serve their country. Many of the best Americans have a strong philanthropic and local community zeal, yet it would seem odd for somebody nowadays to put himself to a big and hard task just to serve his country, to make her better, and be proud of that. Young people aspire mightily to appearances on television and other kinds of notoriety, but I doubt that many now thing of being honoured by a statue in the park and winning “immortal” fame, the fame of big culture. Let me make the same point by analyzing a remarkable proposition of Otto Jespersen, the grammarian. He shows that, contrary to expectation, a child does not learn his mother tongue at home from his mother and immediate family, he does not pick up their accent. The accent, vocabulary, syntax, and styles that form his speech are learned from his first peer groups, outside the home. Jespersen does not explain it, but the psychology seems evident. Speech occurs at the stage of the developing of the “I,” it is a forming of the image of the self, it is a self-appointment to one’s ideal and putting on its uniform. Changes occur as we appoint ourselves to one peer group after another. #RandolphHarris 10 of 21

At certain stage a lad appoints himself or commits himself to a band of friends and puts on its jargon, jacket, tattoo, and masculine ring on the fourth finger of the left hand. If he is insecure and disturbed, this conformity is a cowering protection and the band is a delinquent gang, but in every case it is also, we see by the blazon, an achievement. And one way in which the Governor of California does not take the juveniles seriously, when he speaks of giving them a sense of belonging, is that he does not offer an ideal that promises equal manliness. He has none to offer. It is tragic when there is no great adult peer group to meet growth. Consider the case of an artist, my own case. To have simple and sounding language, rather than merely the lovely colloquialism of Sherwood Anderson or William Carlos Williams, it is necessary to believe in the great national culture of one’s people. Our popular culture does not warrant the belief, even to make the sacrifice that Virgil made when he sadly gave up his best vision because strife-torn Rome needed a national poet. True, an artist can then jump to the international and universal, for a mankind and God do not let him down (mankind is the fellow on one’s own block), but this is at the loss of pomp and glitter, of the glancing present. Without a patriotic peer group, it is impossible to have the brilliance of Handel, the material grandeur of Venice. With us the style of the big bright sensation belongs to cheap musical dramas on Broadway. Now, an analogy to the “triumphant conscience,” as developed by Luther personally as well as theologically, appeared in the enthusiastic philosophy of Giordano Bruno. The moral conscience is overcome by the “heroic affect” toward the Universe and the surrender to its infinity and inexhaustible creativity. Participation in the creativity of life universal liberates the moral conscience, the bad as well as the good. Humans, standing in the center of being, are bound to transform life as it is into higher life. #RandolphHarris 11 of 21

These living souls take upon themselves the tragic consequences, connected with the destructive side of finite creativity, and must not try to escape them for the sake of a good moral conscience. While in Bruno the transmoral conscience is based on a mystical naturalism, Nietzsche’s transmoralism is a consequence of his dramatic-tragic naturalism. Nietzsche belongs to those empiricists who have tried to analyze the genesis of moral conscience in such a way that its autonomy is destroyed—Hobbes and Helvetius, on the ground of a materialistic metaphysics; Mandeville and Bentham, on the ground of a utilitarian psychology; Dr. Darwin and Dr. Freud, on the ground of an evolutionary naturalism—all have denied any objective validity to the voice of conscience, according to their rejection of any universal natural (rational) law. Nietzsche carried these ideas further, as the title and the content of Genealogy of Morals shows. He says, “The bad conscience is a sickness, but it is a sickness as pregnancy is one.” It is a creative sickness. Humankind had to be domesticated, and this has been done by its conquerors and ruling classes. It was in the interest of these classes to suppress by sever punishments the natural instincts of aggressiveness, will to power, destruction, cruelty, revolution. They succeeded in suppressing these trends. However, they did not succeed in eradicating them. So the aggressive instincts became internalized and transformed into self-destructive tendencies. Humans have turned against themselves in self-punishment; they are separated from their innocent terrestrial past from which they had derived strength, joy, and creativity. However, humans cannot prevent their instincts from remaining alive. They require permanent acts of suppression, the result of which is the bad conscience, a great thing in human evolution, an ugly thing if compared with humanities real aim. #RandolphHarris 12 of 21

Nietzsche described this aim in terms which remind one of Luther’s descriptions of the transmoral conscience: “Once in a stronger period than our morbid, desperate present, one must appear, the man of the great love and the great contempt, the creative spirit who does now allow his driving strength to be turned to a transcendent World.” Nietzsche call him the man “who is strong through wars and victories, who needs conquest, adventure, danger, even pain.” The man is “beyond good and evil” in the moral sense. At the same time, he is good in the metaphysical (or mystical) sense that he is in unity with life universal. He has a transmoral conscience, not on the basis of a paradoxical unity with God (such as Luther has), but on the basis of an enthusiastic unity with life in its creative and destructive power. Recent “existential” philosophy has developed a doctrine of transmoral conscience that follows the general lines of Luther, Bruno, and Nietzsche. Heidegger, the main representative of existential philosophy, says, “The call of conscience has the character of the demand that humans in their finitude actualize their genuine potentialities, and this means an appeal to become guilty.” Conscience summons us to ourselves, calling us back from the talk of the market and the conventional behaviour of the masses. It has no special demands; it speaks to us in the “mode of silence.” It tells us only to act and to become guilty by acting, for every action is unscrupulous. One who acts experiences the call of conscience and, at the same time, has the experience of contradicting one’s conscience, of being guilty. “Existence as such is guilty.” Only self-deception can give a good moral conscience, since it is impossible not to act and since every action implies guilt. We must act, and the attitude in which we can act is “resoluteness.” Resoluteness transcends the moral conscience, its arguments and prohibitions. #RandolphHarris 13 of 21

The good, transmoral conscience consists in the acceptance of the bad, moral conscience,which is unavoidable whenever decisions are made and acts are performed. The way from Luther’s to Heidegger’s idea of a transmoral conscience was a dangerous one. “Transmoral” can mean the re-establishment of morality from a point below morality. The empiricists from Hobbes to Dr. Freud have analyzed moral conscience, but they have not destroyed it. Either they were dependent in their concrete ethics on Anglo-Saxon common sense; or they identified utility with the social conventions of a well-established bourgeoisie; or they cultivated a high sense of conscientiousness, in scientific honesty as well as in the fulfillment of duties; or they did not dare, unconsciously or consciously, to draw the radical moral consequences of their dissolution of the conscience. In Nietzsche and Heidegger none of these inhibitions is left. However, it is not without some justification that these names are connected with the antimoral movements of fascism or national socialism. Even Luther has been linked with them, as have Machiavelli and Bruno. This raises the questions: is the idea of a transmoral conscience tenable? Or is it so dangerous that it cannot be maintained? However, if the idea must be dismissed, religion as well as analytic psychotherapy would also have to be dismissed. For in both of them, the moral conscience is transcendent—in religion by the acceptance of the divine grace that breaks through the realm of law and creates a joyful conscience, and in-depth psychology by the acceptance of one’s own conflicts when looking at them and suffering under their ugliness without an attempt to suppress them and to hide them from oneself. Indeed, it is impossible not to transcend the moral conscience because it is impossible to unite a sensitive and good conscience. Those who have a sensitive conscience cannot escape the question of the transmoral conscience. The moral conscience drives beyond the sphere in which it is valid to the sphere from which it must receive its conditional validity. #RandolphHarris 14 of 21

The celibacy movement was rather interesting. The “silent strike,” with its contingent of proud spinsters, generated an inevitable backlash. This came in the form of gender discrimination. Scientists started to expressed the biological differences been men and women. Havelock Ellis said that, “women’s special sphere is the bearing and the rearing of children, with the care of human life in the home. Man’s primary sphere remains the exploration of life outside the home, in industry and inventions and the cultivation of the arts.” With this observation of the status quo cloaked in scientific garb, Ellis proceeded to extrapolate conclusions. One was the ideal the relations involving pleasures of the flesh would be between male dominance and female submissiveness. Another was that the ideal female, a paragon of Motherhood, was very definitely not a spinster, a word that in Ellis’s writings elaborated on the nasty connotations our century has inherited from his. Like so many Motherhood aficionados, Ellis claimed and was credited with a feminist agenda: surely praising the wonderful work of mothers must be women-positive. In Ellis’s case, this seemed irrefutable, for he also preached the novel idea that women should, indeed must, enjoy pleasures of the flesh. No more lying rigid, clenching fists, and teeth, enduring bimonthly intimate invasion by obliterating it with thoughts of England and the empire. (Ironically, Ellis himself had earlier lost an adored lover because he failed to reach a “proud status” during romantic interlude. His predilection in pleasures of the flesh was to observe the other species using the water closet, which stemmed from his unforgettable boyhood experience of watching his mother relieve herself of fluid in the garden.) #RandolphHarris 15 of 21

Ellis’s espousal of the great Motherhood or, in Germany, Mutterschutz, movement particularly explains his enormous influence. From the 1800s onward, fewer children were born but infant mortality soared. Physical exams revealed the poor condition of many schoolchildren, and military recruits were rejected at a high rate for a plethora of disabilities. Something was wrong—at least, these authorities now knew something was wrong—and the solution seemed to be a nation of Super Moms who would reverse the physical decline. In Ellis’s words, these women would undertake the “regeneration of the race” and the “evolution of a supermankind.” Women, too bought into the Motherhood ideal. Some felt it validated the roles they had chosen or that had been chose for them. Others were persuaded that this form of biology was scientific truth and so believed the conclusions its thinkers so convincingly reported. These conclusions clashed with feminist beliefs, particularly the silent strike, the voluntary spinsters’ movement in which women took control of their lives by refusing to surrender their rights to husbands. Censuring spinster became the keynote of antifeminist attacks. One Motherhood proponent, herself a woman, decried spinsters with an analogy to a beehive, in which infertile workers were like “surplus woman” who refused or had no opportunity to marry.  Since the workers bee’s poisoned sting required the egg laying tube, spinsters who relinquished “the power of life” would, by definition, gain possession of “the stinging weapon of death.” Another male antifeminist spoke in alarmist terms of eventual civil war between wives and spinsters, “the waste products of our female population.” In Modern Woman and How to Manager Her, another male writer called spinsters “man-condemning, man-hating…women who are ‘independent of men,’ a motely host, pathetic in their defiance of the first principle of Nature, but of no serious account in the biological sense.” He even proposed polygamy as a solution to “spinsterhood, and the right to live one’s life—the supreme consummation of a large number of revolutionary British women.” #RandolphHarris 16 of 21

In later years, charges of women who lonely loved other women and frigidity, both caused or worsened by spinsterhood, bolstered the attacks on single, independent women. Given that British women outnumbered men by 2 million, this was heavy artillery indeed. The women were acknowledged—negatively—as the prime movers behind reforms for all species, human and animal. The “fanaticism and crankiness” of these dangerous virgins, charged virulent antifeminist Charlotte Haldane, impelled them to espouse “freak science, freak religions, and freak philanthropy,” and to embrace wholeheartedly such contemptible crusades as antivisection, the bane of England’s scientific advancement, dogs’ homes and cats’ homes, missionary endeavors, and “‘Kill-joy’ propaganda.” Furthermore, “enough is known [about the psychological effects of permanent virginity],” Haldane opined, “to make us aware that in entrusted responsibility towards individuals and the State to elderly virgins we may be acting unwisely.” Women and loved other women, styled “intermediate women,” were even more problematic. They should be allowed only inferior jobs because as educators or nurses or doctors, “intermediate women may do an enormous amount of harm.” In the manipulative hands of the “anatomy biologists” and their unlikely Motherhood allies, the celibacy that women seeking independence had once embraced with such delight and firm purpose was now portrayed as sullied and suspicious, a witch’s mantel for freaky madwomen or a masquerade for reviled women who love women. Society still demanded virgin brides, but their virginity was their supreme offering to a husband who would maneuver them through the rest of their life. Aging girls—women—who failed to contract a marriage were pitied, but self-styled spinsters with agendas, no matter how noble and important, were condemned in vitriolic terms, their brand of feminism repudiated as antisocial and unworthy of any regard but the most evil eye. Their celibacy had become as loathsome as its object: women’s independence and personal fulfillment. #RandolphHarris 17 of 21

With so many people in the World today whose outlook is negative, whose emotions are twisted and thinking is warped, it is more needful to stand firm in one’s own spot of optimistic thinking that ever. Whoever doubts the truth of this message, thereby deprives oneself of its benefits. However, this is equally true of the believer who fears its truth. If the future holds distress and suffering, blows and disasters, it is to be met with courage sought and asked from the higher self. According to our faith, it will be given us. It is not a question of what we like or prefer to believe. It is a question of accepting quietly, or else defying vainly, the chose of events and the trend of destiny. If catastrophe and obliteration threaten humanity and if the individual is hopeless when confronted by them, it is logical to conclude that although humanity might not be able to save itself, the individual can save oneself from these disasters if one believes that inner salvation is at least a possibility where outer salvation is not. Yes, you and I can save ourselves from within even when we cannot save ourselves from without. That at least is a better lot than the one of the humans who can save oneself neither from within nor from without and puts one’s faith in political action alone. For politics is merely a system of human bargaining actuated by self-seeking. It can invoke the assistance of no higher power because it does not rise higher than this self-seeking interest itself. However, the individual is free to life oneself above this sordid plane and therefore one is in a position to invite the attention and assistance of higher powers. One who consciously inhabits reality will live independent of the mutations of fate, the catastrophes of history, and the crises of an epoch in dissolution. Even in crisis of war, where danger or even death is lurking, philosophy reveals its immense practicability. For the philosopher can meet them with the utter calmness, effective capacity, and resolute heroism with which one’s studies, reflection, disciplines, and ideals have formed one’s character. #RandolphHarris 18 of 21

Amid the surging tides of postwar chaos, one sets the example and shows the value of philosophic principles by standing firm as a rock. Just as one kept cool in the very midst of global conflagration, so one now keeps clear-sighted amid the gloom of its dusty aftermath. In the very midst of World confusion, one becomes a little oasis of strength and peace, wisdom and certitude, calm and holiness. If one has to live in a chaotic disordered environment, the sad heritage of war, one still lives one’s own constructive ordered pattern of existence. The very example of such a human keeping steady and balanced thus silently helps some others who are bewildered or aimless. Now, when considering American capitalism, there are a few things we should keep in mind. According to Adam Smith, “Labour was the first, price, the original purchase—money that was paid for all things. It was not by gold or by silver, but by labour, that all wealth of the World was originally purchased.” It many come as a surprise that, until field of labour was replaced by factory work, few of our ancestors ever held a job. This surely was not because they were rich. Most were wretchedly poor. They did not hold jobs because the “job,” in today’s sense of formally committed work in return for stipulated pay, had not yet been invented. Like the steam engine and other industrial innovations, jobs and wage labour became widespread only during the last three centuries. Work itself was transferred from outdoors to indoors, or schedules set no longer by sunrise and sunset but by the punch clock. Most payments came in the form of wages based on hours worked. Indeed, these arrangements essentially define the term job. However, the job is only one way of packaging work. And as the latest, knowledge-based wealth systems unfold, we are moving toward a future in which, as we will see, more people “work” but fewer hold “jobs.” #RandolphHarris 19 of 21

It will drastically alter labour relations, human resources departments, legislation and the overall labour market how the offices of employment are conducted in the future. It is bad news for trade unions as we know them. The deep fundamental of work is changing more profoundly than at any time since the industrial revolution. Division of labour, like work itself, traces back to hunting and gathering, when the division was mainly based on gender. However, here, too, we are approaching a turning point. Ever hear of a “metallurgy and failure analysis litigation consultant” or a “post-harvest horticulturalist”? Neither have most of us. (The latter is the superspecialist who determine such things as how many microscopic holes are needed to admit oxygen into the plastic bag that holds vegetables in the supermarket.) Adam Smith in 1776 called the division of labour the source of “the greatest improvement in the productive powers of labour.” And this has been true ever since. However, the more refined and specialized tasks become, the harder and more expensive it becomes to integrate them—especially in an innovation-driven competitive economy. At some point, the costs of integration may exceed the value of such superspecialization. Moreover, narrowly focused specialists may be good at incremental innovation. However, breakthrough innovation is often the product of temporary teams whose members cross disciplinary boundaries—at a time when breakthroughs in every field are, in fact, blurring those very boundaries. And this is not just a matter for scientists and researchers. The new wealth system demands a complete shake-up in the way increasingly temporary skill sets are organized for increasingly temporary purposes throughout the economy. Nothing is more deeply fundamental to the creation of wealthy. Now only are work and the division of labour changing, but income distribution itself—the “who gets what?”—may be heading, over the long term, toward truly revolutionary change. #RandolphHarris 20 of 21

The temple of the animals has fallen into disrepair. The pad of feet has faded. The panthers flee the shadows of the day. Tired, I recall the animals of last year: the altars of the bear, tribunals of the ape, solitudes of elephantine gloom, rare zebra-stripped retreats, prophecies of dog, sanctuaries of the pygmy deer. Were there rituals I had forgotten? Animal calls to which those animal voices replied, called and called until that jungle stirred. Were there voices that I heard? Love was the very animal made his lair, slept out his winter in my heart. Did he seek my hear or ever sleep there? I have seen the animals depart, forgotten their voices, or barely remembered—like that last speech when the company goes or the beloved face that the heart knows, forgets and knows—I have heard the dying footsteps of fall. The sound has faded, but lingers here. Ah, bitterly I recall animals of last year. Thine, O Lord, is the greatness and the power, and the glory and the victory and the majesty; all that is in the Heaven and in the Earth is Thine; Thine is the kingdom, O Lord, and Thou art exalted above all. Both riches and honour come from Thee, and Thou rulest over all; in Thy hand is power and might, and in Thy hand it is to make great, and to give strength unto all. Therefore, our God, we thank Thee, and praise Thy glorious name. O give thanks unto the Lord who alone doeth great wonders; His lovingkindness endureth forever. Sing unto the Lord with thanksgiving; sing praise upon the harp unto our God; He covereth the Heavens with clouds, He prepareth rain for the Earth, and maketh the mountains to be green with grass. He maketh your borders peaceful, He giveth you the fat of the wheat in plenty. He is good to the Earth, and watereth her with His rivers that are full of water. He maketh the Earth soft with showers, and blesseth the growth thereof. He crowneth the year with His goodness, and showereth the Earth with rich bounty. #RandolpHarris 21 of 21

Cresleigh Homes

Stand-out style meets convenience with airy living spaces for sparkling entertainment. 

This Valentines Day, we can’t let the holiday pass by without sharing our love for our new address at Mills Station Residence 1. Amazing home; amazing view; amazing life! 💖💖💖

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