The World has always loved the saint as being the nearest possible approach to the perfection of God. It is unscientific and unscholarly to waste time attempting to prove or disprove things that have already been established beyond question. The true scientist no longer attempts to disprove the pull of gravity, for instance, nor the rotation of the Earth, nor the motion of Heavenly bodies, nor the sequences of the seasons, nor human’s need for food and water, nor the function of the heart. These things are established, and for each individual to bring them into question and insist on going through all the experimentation whereby they have been established would be costly, wasteful, and unfeasible. It is just as unscientific, unscholarly, and even more costly for each individual to insist upon personally conducting the experiments that have proved that sin brings sorrow, that disbelief brings emptiness and unrest, that things forbidden of God are not good for human, that the use of illegal substances are enslaving habits, that unchastity brings unhappiness, and so forth. Religion and science have sometimes appeared in conflict. Yet, the conflict can only be apparent, not real, for science seeks truth, and true religion is truth. There can never be conflict between revealed religion and true science. #RandolphHarris 1 of 10

Truth is truth, whether labeled science or religion. All truth is consistent. There is no conflict—only in the interpretation of fact. Studies of high-altitude residents have greatly contributed to our understanding of physiological adaptation. As you would expect, altitude studies have focused on inhabited mountainous regions, particularly in the Himalayas, Andes, and Rocky Mountains. Of these three areas, permanent human habitation probably has the longest history in the Himalayas. Today, perhaps as many as 25 million people live at altitudes above 10,000 feet. In Tibet, permanent settlements exist above 15,000 feet, and in the Andes, they can be found as high as 17,000 feet. Because the mechanisms that maintain homeostasis in human evolved at lower altitudes, they are compromised by the conditions at higher elevations. At high altitudes, many factors produce stress on the human body. These include hypoxia (reduced available oxygen), more intense solar radiation, cold, low humidity, wind (which amplifies cold stress), a reduced nutritional base, and rough terrain. Of these, hypoxia exerts the greatest amount of stress on human physiological systems, especially the heart, lungs, and brain. #RandolphHarris 2 of 10

Hypoxia results from reduced barometric pressure. It is not that there is less oxygen overall in the atmosphere at high altitudes; rather, it is less concentrated. Therefore, to obtain the same amount of oxygen at 9,000 feet as at sea level, people must make certain physiological alterations aimed at increasing the body’s ability to transport and efficiently use the oxygen that is available. At high altitudes, reproduction, in particular, is affected through increased infant mortality rates, miscarriage, low birth weights, and premature birth. An early study reported that in Colorado, infant deaths are almost twice as common above 8,200 feet (2,500 meters) as at lower elevations. One cause of fetal and maternal death is preeclampsia, a severe elevation of blood pressure in pregnant women after the twentieth gestational week. People born at lower altitudes and high-altitude natives differ somewhat in how they adapt to hypoxia. Upon exposure to high altitude people born at low elevation become acclimatized. The responses may be short-term modifications, depending on duration of stay, but they begin within hours of the altitude change. These changes include an increase in respiration rate, heart rate, and production of red blood cells. (Red blood cells contain hemoglobin, the protein responsible for transporting oxygen to organs and tissues.) #RandolphHarris 3 of 10

A more permanent, developmental acclimatization occur in high-altitude natives during growth and development. This type acclimatization is present only in people who grow up in high-altitude areas, not in those who moved there as adults. Compared with populations at lower elevations, life-long residents of high altitudes display slowed growth and maturation. Other differences include larger chest size, associated, in turn, with greater lunch volume and larger heart. In addition to greater lung capacity, people born at high are more efficient than migrants at diffusing oxygen from blood to body tissues. Developmental acclimatization to high-altitude hypoxia serves as a good example of physiological plasticity by illustrating how, within the limits set by genetic factors, development can be influenced by environment. There is evidence that entire populations have also genetically adapted to high altitudes. Indigenous peoples of Tibet who have inhabited regions higher than 12,000 feet for around 25,000 years may have made genetic (i.e,. evolutionary) accommodations to hypoxia. Altitude does not appear to affect reproduction in these people to the degree it does in other populations. Infants have birth weights as high as those of lowland Tibetan groups and higher than those of recent (20 to 30 years) Chinese immigrants. This fact may be the result of alterations in maternal blood flow to the uterus during pregnancy. #RandolphHarris 4 of 10

Another line of evidence concerns how the body processes glucose (blood sugar). Glucose is critical because it is the only source of energy used by the brain, and it is also used, although not exclusively, by the heart. Both highland Tibetans and the Quechua (inhabitants of high-altitude regions of the Peruvian Andes) burn glucose in a way that permits more efficient use of oxygen. This implies the presence of genetic mutations in the mitochondrial DNA (mtDNA directs how cells use glucose). It also implies that natural selection has acted to increase the frequency of these advantageous mutations in these groups. As yet, there is no certain evidence that Tibetans and Quechua have made evolutionary changes to accommodate high-altitude hypoxia (since specific genetic mechanisms that underlie these populations’ unique abilities have not been identified). However, current data strongly suggest that selection has operated to produce evolutionary change in these two groups. If further study supports these findings, we have an excellent example of evolution in action producing long-term adaptation at the population level. “Trust in the Lord with all thine heart; and lean not unto thine own understanding. It all thy ways acknowledge God, and he shall direct thy paths,” reports Proverbs 3.5-6. #RandolphHarris 5 of 10

Speaking of high elevations, Cosmonauts that spend long months aboard the International Space Station lose bone strength faster than previously thought and have a higher risk of breaking their hips later in life. A survey of 13 space station cosmonauts found that their bone strength dipped by at least 14 percent on the average during their half-year stays aboard the orbiting laboratory. Three of the cosmonauts lost up to 30 percent of their bone strength during their long-duration spaceflights, putting them on par with the bone strength of elderly people with osteoporosis on Earth. If preventive measures are not taken, some of our cosmonauts may be at increased risk for age-related fractures decades after their missions. When in space, bone mineral density can decrease by between 0.6 percent and 5 percent each month. Cosmonauts gradually lose muscle strength and bone density over time while on long-duration spaceflights because their bodies float in microgravity, rather than work against the tug of Earth’s gravity each day. To lessen the effects, space station cosmonauts must exercise at least two hours every day and undergo weeks of rehabilitation after their return to Earth. #RandolphHarris 6 of 10

The hip and spine of long duration cosmonauts typically experience the greatest amount of bones loss. Hip fractures nearly always require hospitalization or major surgery, while vertebra fractures in the spine can lead to loss of height, severe back pain and deformity. When people make new discoveries in their energetic search for truth, it is well to remember these will always be in harmony with all fundamental and eternal truths. Yes, truth is always consistent, whether it is revealed directly from God to humans, through his inspired prophets, or comes from the laboratory through diligent searching of his children and through the influence of the Spirit of the Lord upon them. This quest for wisdom or intelligence, which the Lord defines as light and truth, is a glorious challenge. We have been assured by the Author of Eternal Life that whatever principle of intelligence we attain unto this life, it will rise with us in the resurrection. So there seems to be a motive to learn all we can while on Earth. “And if a person gains more knowledge and intelligence in this life through one’s diligence and obedience than another, one will have so much the advantage in the World to come,” reports Doctrines and Covenants 130.18-19. #RandolphHarris 7 of 10

We are in a changing World beset with many perplexities. However, while change is all about us, and will continue to be, in the physical World, we must recognize that there are certain Heaven-sent verities, principles, and values that are eternal. These never change. As we travel life’s highway, we will encounter theories, proposals, and programs that have wide appeal. One of many fascinating concepts is marginal benefit. Marginal benefit is an increase in an activity’s overall benefit that is caused by a unit increased in the level of that activity, all other factors remaining constant. Marginal decision making can help explain some otherwise puzzling economic phenomena. For instance, why is water so inexpensive, while gold is so expensive? Humans, animals, and plants need water to survive, while gold is relatively unnecessary; but for some reason, people are willing to pay much more for a bar of gold than for a cup of water. The reason is that a person’s willingness to pay for any good is based on the marginal benefit that an extra unit of the good would yield. The marginal benefit, in turn, depends on how many units a person already has. Although water is essential, the marginal benefit of an extra cup is small because water is plentiful. By contrast, no one needs gold to survive, but because gold is so rare, people consider the marginal benefit of an extra bar of gold to be large. #RandolphHarris 8 of 10

Be not mislead. A rational decision maker takes an action if and only if the marginal benefit of the action exceeds the marginal cost. This principle can explain why people are more willing to pay more for diamonds than for water, or why some builders are willing to sell a house below average cost. It can take some time to get used to the logic of marginal thinking, but the study of economics will give one ample opportunity to practice. Remember that ideas and theories are either sound or unsound; their soundness does not depend upon which people hold them. Be mindful that there are also many phenomena in God’s Universe that cannot, to our present human understanding, be explained. There will always be those little minds who, out of vanity or intellectual display, will attempt to destroy faith in the very foundations of life. Be assured, however, that no one, worthy of the name, who has been humped and awed before the unexplainable wonders of this marvelous Universe, will ever scoff at sacred things or try to rob you of your faith in the unseen. Our inability to explain things, like spirituality, in terms of our materialism does not disprove its reality. #RandolphHarris 9 of 10

By yielding obedience to your faith in God and the laws of the Universe, both spiritual and physical, there will come a soul-satisfying security that is priceless. You will need this anchor as you face a doubting World. Advance unafraid! Meet the challenge of a modern World. In doing so, beware of the philosophy which suggests that morality is out of date—that virtue, chastity, marriage, and honorable family life are throwbacks to a Victorian age. These are eternal principles—as eternal as life itself. Remember, it is truth that endures. It is truth that makes people courageous enough to become Christlike. It is the truth that makes people and nations free. Yes, be intelligent. Intelligence is wise and judicious use of knowledge. Continue to grow mentally—to grow in wisdom—to grow in truth. Desire it! Pray for it! Study! Practice it! Do all this and you will find true; it cannot be denied you. Having found it, never forget its source. “The glory of God is intelligence, or, in other words light and truth,” reports Doctrine and Covenants 93.36. Be worthy trustees of Earth. Continue to grow in stature. Be cheerful in all that you do. Live joyfully. Live happily. Live enthusiastically, knowing that God does not dwell in gloom and melancholy, but in light and love. #RandolphHarris 10 of 10